Dysport Before and After, Day by Day

Reviewed for medical accuracy against our Medical Review Board  ·  Last updated 23 August 2026

Dysport's own trial data tracks results from day 14 to day 180, and it says three things the photo galleries do not. Results peak at day 14, not day 30. "Up to four months" applies to a minority: by day 120 only 23% were still rated clear or nearly clear. And patients scored their own results 13 to 14 points lower than investigators scored the same faces, which is the measured reason clinic photos look better than your mirror.

A gloved hand holding four small glass vials, each with a graduated syringe inserted, against a plain background
Not a treatment result. The figures on this page come from three trials of 376 treated patients, because we publish the data rather than photographs of strangers.

We do not publish before and after photographs. We have no clinical photo library, and putting stock images of strangers on a page about results would be dishonest. What we can do is show you the numbers behind what a real result looks like, and explain how to read the photos a clinic shows you.

1. The day-by-day curve, from the trials

This is Table 17 of the Dysport prescribing information, from study GL-1: 105 people treated with 50 units for frown lines, 53 on placebo, followed for 180 days. The figures are the percentage rated none or mild for glabellar line severity at maximum frown.

Percentage at none or mild severity at maximum frown, study GL-1
DayInvestigator, Dysport Investigator, placeboPatient, Dysport Patient, placebo
1490%17%77%9%
3088%4%74%9%
6064%2%60%6%
9043%6%36%6%
12023%4%19%6%
1509%2%8%4%
1806%not reportednot reportednot reported

Almost everything worth knowing about Dysport results is in that table, and it is on page 24 of a document nobody reads.

2. Results peak at day 14

The highest figure in the whole dataset is day 14, at 90% by the investigator's assessment and 77% by the patient's. Day 30 is marginally lower. Everything after that declines.

Two things follow. First, if you are judging your result, day 14 is the right day. Earlier and it has not finished; later and it has started to fade. This is also why a two week review appointment is the industry norm rather than a sales device.

Second, the popular claim that Dysport "works in two to three days" is not in the label at all. The earliest measurement in these trials is day 14, and the label's primary endpoint is day 30. Something is usually happening by day three in practice, and injectors observe it consistently, but it is clinical convention rather than a labelled figure. Our page on how long Dysport lasts goes through the onset question in detail.

3. Why the doctor sees a better result than you do

This is the finding we did not expect, and it is measured rather than theorised.

At every single time point, patients rated their own results lower than the investigators rated the same faces. At day 14 the gap is 13 points, 90% against 77%. At day 30 it is 14 points, 88% against 74%. The gap narrows later as everyone agrees the effect is fading.

Nobody is wrong here. Both groups used the same four-point scale on the same faces, and the label reports both because the primary endpoint required them to agree. It is simply the case that the person who sees your face every day in the mirror is a harder marker than the clinician seeing you every few weeks.

The practical value of that is real. If your injector says your result looks great and you are less sure, you are both probably reporting accurately, and a 13 point systematic gap is the expected outcome rather than a sign of being fobbed off. It is also the honest explanation for why clinic photographs consistently look better than your own reflection: they are graded by the person on the flattering side of that gap, in good lighting, at peak.

4. How often it works at all

The three glabellar trials measured "treatment success" on a deliberately demanding endpoint: a severity of none or mild, and at least a two grade improvement from baseline, and at maximum frown, and agreed by both the investigator and the patient.

Treatment success at day 30, composite endpoint, all three glabellar studies
StudyDysportPlacebo
GL-158 of 105 (55%)0 of 53 (0%)
GL-237 of 71 (52%)0 of 71 (0%)
GL-3120 of 200 (60%)0 of 100 (0%)
All three combined215 of 376 (57%) 0 of 224 (0%)

So roughly four in ten people did not meet that bar. That is not a failure rate in any ordinary sense: plenty of those people improved, just not by two full grades at maximum frown with both assessors agreeing. Look at the softer measure in the first table and 90% were at none or mild by day 14.

The number is still worth carrying into a consultation, because it is the honest counterweight to a photo wall. Somewhere between a third and a half of people get a result more modest than the pictures you are shown, and the pictures are not fake. They are the top of the distribution.

5. The placebo column, which is the real proof

Look again at the placebo column above: zero out of 224. Across three trials, not a single person given a placebo injection hit the composite endpoint.

That is an unusually clean result for an aesthetics product, and it is the strongest evidence on this page. It rules out the explanations that usually complicate cosmetic trials. It is not people convincing themselves, not the massage of being injected, not regression to the mean. In the softer day 14 measure, 17% of placebo patients were rated none or mild by an investigator, which shows the scale has some give in it. On the strict endpoint, nobody on placebo qualified at all.

Whatever else is uncertain about Dysport, that it works on frown lines is not.

6. What "up to four months" actually means

The label says treatment "reduced the severity of glabellar lines for up to four months," and every clinic repeats it. The day-by-day table shows what it is built on.

Day 120 is four months. At day 120, 23% were still rated none or mild by the investigator and 19% by themselves. So four months is real, and it describes roughly one person in five.

The median tells a different story. By day 90, three months, the investigator figure is 43% and the patient figure 36%, so the typical person has lost half the effect by then. That matches the label's other instruction, which is that Dysport should be given no more often than every three months: the minimum interval and the point at which most people notice it fading are the same date, which is not a coincidence.

Planning on three treatments a year is realistic. Planning on four months of full effect is optimistic for most people. The cost page works the annual arithmetic through.

7. What to expect, week by week

If you want to track your own, photograph yourself at maximum frown, in the same light, at day 0 and day 14. Maximum frown matters: that is what the trials measured, and a photograph at rest will show you much less difference because much of what you see at rest is skin rather than muscle.

8. How to read a clinic's before and after photos

Clinic photographs are usually real and still misleading, for reasons that have nothing to do with dishonesty. What to check:

  1. Is the "after" at maximum frown, like the "before"? The commonest distortion is a hard frown before and a relaxed face after. That comparison is meaningless.
  2. Same lighting, angle and distance? Overhead light exaggerates lines. Flat frontal light erases them. A change of lighting alone can produce a convincing before and after with no treatment at all.
  3. How many days after? If it does not say, assume day 14, the peak.
  4. Makeup in the "after" only? Very common, rarely mentioned.
  5. Was anything else done? Filler, resurfacing or a peel in the same period changes what you are looking at.
  6. How many cases are shown? Ten photographs from a clinic that treats a thousand people a year are the top 1%, and given that 57% met the trial endpoint, a gallery where everyone is transformed is not a representative sample.

None of this means do not look at them. It means ask "how many units, which brand, and how many days after" for any photograph you find persuasive. A clinic that can answer instantly is telling you something good about its record-keeping.

9. Other areas, and why there is no data

Every figure on this page is for frown lines, because that is the only cosmetic area Dysport is approved for and the only one with trial data. Searches for Dysport before and after on the forehead, crow's feet, a lip flip or the jaw are asking about off-label uses, where no manufacturer has published an efficacy dataset at all.

What carries across is the shape of the curve: onset over the first week, peak around two weeks, noticeable fade by three months. What does not carry across is the success rate, and two areas are genuinely different. A lip flip fades faster than frown lines, often noticeably by six to eight weeks. Masseter slimming is far slower, because the change comes from a thick muscle reducing in bulk over months rather than a line relaxing, so a two week photograph of a jawline shows almost nothing. Our page on Dysport treatment areas covers each one.

10. When it will not work, and you can predict it

The trials excluded people with "a substantial inability to lessen glabellar lines, even by physically spreading them apart." That exclusion is a free self-test, and it is the most useful sentence in the label for anyone about to spend money.

Put a fingertip either side of the line between your brows and gently pull the skin apart. If the line disappears, it is being held by muscle and a toxin will treat it. If the line is still there with the skin stretched flat, it is etched into the skin itself, and no dose of any botulinum toxin at any price will remove it. That needs resurfacing, filler or time.

The people who post that Dysport did nothing for them are very often people whose lines would have failed that test. It is worth doing before you book rather than after you pay. Our page on frown lines and the glabella covers what each option actually does, and the myths page covers the rest of the expectations that get set wrongly.

Two other predictors from the label. Marked existing ptosis and deep dermal scarring were both exclusion criteria. And the trials enrolled adults aged 19 to 75, but the cosmetic indication is written for adults under 65, so if you are older than that you are outside the approved population for the one cosmetic use it is approved for.

Frequently asked questions

When will I see Dysport results?
Movement usually feels different within three to seven days, and the visible result peaks around day 14. In study GL-1, 90% of treated subjects were rated none or mild for frown line severity at day 14 by investigators, and 77% by the patients themselves. Day 30 was marginally lower. The widely repeated claim that Dysport works in two to three days is clinical observation rather than a labelled figure: the earliest measurement in the trials is day 14.
When is the best time to take an after photo?
Day 14, because that is when the trial data peaks. Photograph yourself at maximum frown rather than at rest, in the same lighting and from the same angle as your before photo. Maximum frown is what the trials measured, and a photo at rest shows much less difference because a lot of what you see at rest is skin texture rather than muscle activity.
How long do Dysport results last?
The label says up to four months, and the day-by-day data shows what that means: at day 120 about 23% were still rated none or mild by an investigator and 19% by themselves. So four months applies to roughly one person in five. The typical experience is losing about half the effect by day 90, which is also the earliest the label allows re-treatment. Three treatments a year is the realistic plan.
Does Dysport actually work?
On frown lines, yes, and the evidence is unusually clean. Across the three glabellar trials, 215 of 376 treated patients hit a demanding composite endpoint at day 30, while 0 of 224 placebo patients did. Not one person on placebo qualified. That rules out the explanations that usually muddy cosmetic trials, such as expectation or the effect of being injected at all.
Why do only about half of people meet the trial success bar?
Because the bar was set high on purpose. Success required severity of none or mild, plus at least a two grade improvement from baseline, at maximum frown, with the investigator and the patient both agreeing. On a softer measure in the same study, 90% were at none or mild by day 14. So the 57% figure is not a failure rate; it is the proportion achieving a large, unambiguous, independently agreed change.
Why does my result look worse to me than to my injector?
Because that gap is real and measured. At every time point in the trials, patients rated their own results lower than investigators rated the same faces, by 13 points at day 14 and 14 points at day 30. Neither party is wrong: the person who sees their own face daily is simply a harder marker. It is also why clinic photographs tend to look better than your mirror, since they are graded from the generous side of that gap, in good light, at peak.
Are clinic before and after photos trustworthy?
Usually genuine and still easy to misread. The commonest distortion is a hard frown in the before photo and a relaxed face in the after, which compares nothing. Lighting alone can create a convincing result with no treatment. Ask three questions of any photo that persuades you: how many units, which brand, and how many days after. Also remember a gallery of ten transformations from a clinic treating hundreds of people is the top of the distribution, not the middle.
Is there before and after data for the forehead or crow's feet?
No published efficacy dataset exists, because frown lines are the only cosmetic area Dysport is approved for and the only one that was trialled. Forehead, crow's feet, brow lift, lip flip and masseter are all off-label. The timing pattern generally carries across, with onset in the first week and a peak around two weeks, but the success rates do not, and two areas differ sharply: a lip flip fades faster, often by six to eight weeks, and masseter slimming is far slower because it depends on muscle bulk reducing over months.
How can I tell in advance whether Dysport will work on my lines?
There is a free test, taken from the trials' own exclusion criteria. Put a fingertip either side of the line between your brows and gently pull the skin apart. If the line disappears, it is held by muscle and a toxin will treat it. If it is still visible with the skin stretched flat, it is etched into the skin and no dose of any botulinum toxin will remove it, because that needs resurfacing, filler or time. People excluded from the trials for exactly this reason are a good share of those who report that Dysport did nothing.
Will my second treatment work better than my first?
Often it looks better, though not because your body responds differently. Your injector now knows how your muscles actually behaved at your dose, which is the single biggest variable. The label also reports continued efficacy across up to four repeated treatments, and separately that antibody formation is not a practical concern in cosmetic dosing: across 1,554 patients treated up to nine times, none developed a neutralising antibody.
Do results look better at day 30 than day 14?
Slightly worse, by the trial data: investigator ratings were 90% at day 14 and 88% at day 30, with patient ratings at 77% and 74%. The difference is small enough that both days look like your result. The label uses day 30 as its primary endpoint, which is why day 30 figures are quoted more often, but the peak is two weeks.
Why do you not show before and after photos?
Because we have no clinical photo library, and using stock photographs of strangers on a page about results would be presenting something as evidence when it is not. We would rather give you the manufacturer's own day-by-day dataset, which no competing page uses, and the tools to read the photos your clinic shows you. If we ever publish photographs they will be real, sourced, and captioned with the brand, the units and the number of days.
Lucas Pradella, founder of BestBotoxClinics.com

Written by

Lucas Pradella

Founder & Lead Researcher, BestBotoxClinics.com

Lucas founded BestBotoxClinics.com to bring clarity to the aesthetics industry, bringing 13+ years of experience in digital research and analysing online data for signals of quality and trust. He is not a physician, his work is research, data analysis and verifying provider credentials.

Medical accuracy: BestBotoxClinics.com maintains a Medical Review Board of licensed clinicians. This article is educational and is not medical advice.